Structure of PDB 7h4m Chain A

Receptor sequence
>7h4mA (length=139) Species: 31704 (Coxsackievirus A16) [Search protein sequence]
SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARC
DCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSE
PGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDE
3D structure
PDB7h4m Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease
ChainA
Resolution1.42 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 O3A A F83 L100 T126 G128 N129 L131 F77 L94 T120 G122 N123 L125
BS02 ZN A C56 C58 C116 H118 C50 C52 C110 H112
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7h4m, PDBe:7h4m, PDBj:7h4m
PDBsum7h4m
PubMed
UniProtQ65900|POLG_CX16G Genome polyprotein

[Back to BioLiP]