Structure of PDB 7h4c Chain A

Receptor sequence
>7h4cA (length=140) Species: 31704 (Coxsackievirus A16) [Search protein sequence]
SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARC
DCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSE
PGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEE
3D structure
PDB7h4c Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease
ChainA
Resolution1.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VW4 A H25 W28 H19 W22
BS02 VW4 A V84 S105 E106 P107 T126 G127 V78 S99 E100 P101 T120 G121
BS03 ZN A C56 C58 C116 H118 C50 C52 C110 H112
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

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Molecular Function
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Biological Process
External links
PDB RCSB:7h4c, PDBe:7h4c, PDBj:7h4c
PDBsum7h4c
PubMed
UniProtQ65900|POLG_CX16G Genome polyprotein

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