Structure of PDB 7fup Chain A

Receptor sequence
>7fupA (length=357) Species: 9606 (Homo sapiens) [Search protein sequence]
MGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLL
NTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKE
NPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMRKRGGSPAVTL
LISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLV
PKHAKGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLM
KYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLC
FDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERN
NEFPVFD
3D structure
PDB7fup Crystal Structure of a human cyclic GMP-AMP synthase complex
ChainA
Resolution2.411 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.86: cyclic GMP-AMP synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H390 C396 C397 C404 H227 C233 C234 C241
External links
PDB RCSB:7fup, PDBe:7fup, PDBj:7fup
PDBsum7fup
PubMed
UniProtQ8N884|CGAS_HUMAN Cyclic GMP-AMP synthase (Gene Name=CGAS)

[Back to BioLiP]