Structure of PDB 7ful Chain A

Receptor sequence
>7fulA (length=354) Species: 9606 (Homo sapiens) [Search protein sequence]
ASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNT
GSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENP
LSQFLEGEILSASKMLSKFRKIIKEEINDDTDVIMKRKPAVTLLISEKIS
VDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEG
NGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLL
EQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNC
VTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFP
VFDE
3D structure
PDB7ful Crystal Structure of a human cyclic GMP-AMP synthase complex
ChainA
Resolution2.296 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.86: cyclic GMP-AMP synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H390 C397 C404 H223 C230 C237
BS02 YUO A K362 S378 F379 S380 E383 Y436 T440 F443 Y483 F484 K195 S211 F212 S213 E216 Y269 T273 F276 Y316 F317
External links
PDB RCSB:7ful, PDBe:7ful, PDBj:7ful
PDBsum7ful
PubMed
UniProtQ8N884|CGAS_HUMAN Cyclic GMP-AMP synthase (Gene Name=CGAS)

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