Structure of PDB 7fty Chain A

Receptor sequence
>7ftyA (length=352) Species: 9606 (Homo sapiens) [Search protein sequence]
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLN
TGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKEN
PLSQFLEGEILSASKMLSKFRKIIKEEINDIDVIMKRKRGGSPAVTLLIS
EKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKH
AKQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLE
QLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCV
TYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPV
FD
3D structure
PDB7fty Crystal Structure of a human cyclic GMP-AMP synthase complex
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.86: cyclic GMP-AMP synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H390 C397 C404 H222 C229 C236
BS02 YQZ A R376 L377 F379 S380 E383 Y436 F443 N482 F484 F488 L490 R208 L209 F211 S212 E215 Y268 F275 N314 F316 F320 L322
External links
PDB RCSB:7fty, PDBe:7fty, PDBj:7fty
PDBsum7fty
PubMed
UniProtQ8N884|CGAS_HUMAN Cyclic GMP-AMP synthase (Gene Name=CGAS)

[Back to BioLiP]