Structure of PDB 7fiz Chain A

Receptor sequence
>7fizA (length=779) Species: 172827 (Meiothermus taiwanensis) [Search protein sequence]
RLELPVIPLRNTVILPHTTTPVDVGRAKSKRAVEEAMGADRLIFLVAQRD
PEVDDPAPDDLYTWGVQAVVKQAMRLPDGTLQVMVEARARAQVTDYIPGP
YLRARGEVFSEIFPIDEAVVRVLVEELKEAFEKYVANHKSLRLDRYQLEA
VKGTSDPAMLADTIAYHATWTVAEKQEILELTDLEARLKKVLGLLSRDLE
RFELDKRVAQRVKEQMDTNQREYYLREQMKAIQKELGGEDGLSDLEALRK
KIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDWLTEVPWSKA
DPEVLDINHTRQVLDEDHYGLKDVKERILEYLAVRQLTQGLDVRNKAPIL
VLVGPPGVGKTSLGRSIARSMNRKFHRISLGGVRDEAEIRGHRRTYIGAM
PGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEVLDPEQNNTF
TDHYLDVPYDLSKVFFITTANTLQTIPRPLLDRMEVIEIPGYTNMEKQAI
ARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTREAGVRGLERELGKIA
RKGAKFWLEGAWEGLRTIDASDIPTYLGIPRYRPDKAETEPQVGTAQGLA
WTPVGGTLLTIEVAAVPGSGKLSLTGQLGEVMKESAQAALTYLRAHTQDY
GLPEDFYNKVDLHVHVPDGATPKDGPSAGITMATAIASALSRRPARMDIA
MTGEVSLRGKVMPIGGVKEKLLAAHQAGIHKIVLPKDNEAQLEELPKEVL
EGLEIKLVEDVGEVLEYLLLPEPTMPPVV
3D structure
PDB7fiz Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
ChainA
Resolution3.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.53: endopeptidase La.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I398 W431 I397 W430
BS02 AGS A H319 G358 V359 G360 K361 S363 Y493 I501 V540 R541 H318 G357 V358 G359 K360 S362 Y492 I500 V539 R540
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0008236 serine-type peptidase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0030163 protein catabolic process
GO:0034605 cellular response to heat
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7fiz, PDBe:7fiz, PDBj:7fiz
PDBsum7fiz
PubMed34757797
UniProtA0A059VAZ3

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