Structure of PDB 7fhk Chain A

Receptor sequence
>7fhkA (length=663) Species: 3702,6100 [Search protein sequence]
RVRRSEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIF
TRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTN
AESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDV
LVDFLYLFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALW
MLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIP
AYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMK
RRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFD
ELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQL
RAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGW
IYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPDENTF
FSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIF
CVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTL
FNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLE
AFFTELDLEEEEK
3D structure
PDB7fhk Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L375 R398 L352 R375
BS02 CA A D335 D337 N339 E341 D312 D314 N316 E318
BS03 CA A D454 E528 D431 E505
BS04 CA A E239 D240 E216 D217
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005216 monoatomic ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0042802 identical protein binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006811 monoatomic ion transport
GO:0006816 calcium ion transport
GO:0008218 bioluminescence
GO:0009845 seed germination
GO:0010119 regulation of stomatal movement
GO:0019722 calcium-mediated signaling
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0080141 regulation of jasmonic acid biosynthetic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005575 cellular_component
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7fhk, PDBe:7fhk, PDBj:7fhk
PDBsum7fhk
PubMed34845029
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q94KI8|TPC1_ARATH Two pore calcium channel protein 1 (Gene Name=TPC1)

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