Structure of PDB 7ff0 Chain A

Receptor sequence
>7ff0A (length=206) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
KLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDG
REMIIGYLNSGDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFR
ELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQ
PDAMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTM
VVFGTR
3D structure
PDB7ff0 Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A I51 I63 F72 G73 E74 L75 R87 S88 A89 R128 I43 I55 F64 G65 E66 L67 R79 S80 A81 R120
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001216 DNA-binding transcription activator activity
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0030552 cAMP binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ff0, PDBe:7ff0, PDBj:7ff0
PDBsum7ff0
PubMed37007650
UniProtP55222|VFR_PSEAE cAMP-activated global transcriptional regulator Vfr (Gene Name=vfr)

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