Structure of PDB 7fav Chain A

Receptor sequence
>7favA (length=269) Species: 11044 (Rubella virus vaccine strain RA27/3) [Search protein sequence]
PRGCQGCELCRYTRVTNDRAYVNLWLERDRGATSWAMRIPEVVVYGPEHL
ATHFPLNHYSVLKPAEVRPPRGMCGSDMWRCRGWQGVPQVRCTPSNAHAA
LCRTGVPPRVSTRGGELDPNTCWLRAAANVAQAARACGAYTSAGCPRCAY
GRALSEARTHKDFAALSQRWSASHADASSDGTGDPLDPLMETVGCACSRV
WVGSEHEAPPDHLLVSLHRAPNGPWGVVLEVRARPEGGNPTGHFVCAVGG
GPRRVSDRPHLWLAVPLSR
3D structure
PDB7fav Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold.
ChainA
Resolution1.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1034 C1037 C1040 H1088 C4 C7 C10 H58
BS02 ZN A C1175 C1178 C1225 C1227 C145 C148 C195 C197
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:7fav, PDBe:7fav, PDBj:7fav
PDBsum7fav
PubMed35835220
UniProtO40955|POLN_RUBVR Non-structural polyprotein p200

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