Structure of PDB 7f9v Chain A

Receptor sequence
>7f9vA (length=479) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
TAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDD
EIKKMGVENSYFPMFVSRHKLEKEFSPEVAWVTHYGDSPLPEKIAIRPTS
ETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEG
HTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKT
TTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWG
CTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCR
ELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGT
ARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKIS
TFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIMTGAMKTLCIP
FDQPPMPEGTKCFYTGKPAKRWTLWGRSY
3D structure
PDB7f9v TgPRS with double inhibitors
ChainA
Resolution1.816 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1TI A E472 K474 Q475 P476 L480 R481 T482 F485 Q555 A556 A557 G590 T592 R594 E132 K134 Q135 P136 L140 R141 T142 F145 Q215 A216 A217 G250 T252 R254
BS02 HFG A F415 E418 V419 P438 T439 E441 R470 W487 F534 H560 F75 E78 V79 P98 T99 E101 R130 W147 F194 H220
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f9v, PDBe:7f9v, PDBj:7f9v
PDBsum7f9v
PubMed
UniProtA0A7J6JUK2

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