Structure of PDB 7f9s Chain A

Receptor sequence
>7f9sA (length=484) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
TAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDD
EIKKMGVENSYFPMFVSRHKLEKFSPEVAWVTHYGDSPLPEKIAIRPTSE
TIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGH
TAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTT
TVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGC
TTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRE
LKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTA
RVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKIST
FDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEAGMTGAMK
TLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY
3D structure
PDB7f9s TgPRS with double inhibitors
ChainA
Resolution1.861 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1TI A E472 K474 Q475 P476 L480 R481 T482 F485 Q555 A556 A557 G590 T592 R594 E131 K133 Q134 P135 L139 R140 T141 F144 Q214 A215 A216 G249 T251 R253
BS02 9SF A F415 P438 T439 E441 R470 W487 F534 H560 S588 W589 F74 P97 T98 E100 R129 W146 F193 H219 S247 W248
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f9s, PDBe:7f9s, PDBj:7f9s
PDBsum7f9s
PubMed
UniProtA0A7J6JUK2

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