Structure of PDB 7f97 Chain A

Receptor sequence
>7f97A (length=487) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAF
FNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLP
EEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIR
TREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEG
EKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVK
QYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTD
ENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEV
GPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKK
LDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLLSG
AMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY
3D structure
PDB7f97 Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with L-proline and compound L97
ChainA
Resolution2.394 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.15: proline--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO A T359 E361 W407 E409 F454 H480 S508 W509 G510 T108 E110 W156 E158 F203 H229 S257 W258 G259
BS02 1XK A R390 E392 K394 Q395 P396 I400 R401 T402 F405 W407 Q475 A477 T478 G510 T512 R514 R139 E141 K143 Q144 P145 I149 R150 T151 F154 W156 Q224 A226 T227 G259 T261 R263
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f97, PDBe:7f97, PDBj:7f97
PDBsum7f97
PubMed
UniProtQ8I5R7|SYP_PLAF7 Proline--tRNA ligase (Gene Name=proRS)

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