Structure of PDB 7f7g Chain A

Receptor sequence
>7f7gA (length=186) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SEFVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDG
RDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCI
LDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRA
TKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSG
3D structure
PDB7f7g Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
ChainA
Resolution2.446 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D545 V563 P564 R568 R571 D579 Y580 E600 Q603 Y604 Y609 G610 T611 D629 D18 V36 P37 R41 R44 D52 Y53 E73 Q76 Y77 Y82 G83 T84 D102
External links
PDB RCSB:7f7g, PDBe:7f7g, PDBj:7f7g
PDBsum7f7g
PubMed34458841
UniProtP31016|DLG4_RAT Disks large homolog 4 (Gene Name=Dlg4)

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