Structure of PDB 7f6w Chain A

Receptor sequence
>7f6wA (length=506) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYAHLKKGET
LPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYE
KDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPA
FKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETP
MMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIG
RQFRNEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEITGSY
IIKYHPDPADPAKELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAE
TGEFLKKILVDNKLECPPPLTNARMLDKLVGELEDTCINPTFIFGHPQMM
SPLAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQK
DQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLL
FPTLKP
3D structure
PDB7f6w Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex.
ChainA
Resolution2.607 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.6: lysine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KAA A E304 R326 H334 N335 F338 E342 E497 I498 N500 Y502 E504 G549 G553 R556 E232 R254 H262 N263 F266 E270 E425 I426 N428 Y430 E432 G477 G481 R484
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004824 lysine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006430 lysyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f6w, PDBe:7f6w, PDBj:7f6w
PDBsum7f6w
PubMed35133502
UniProtP15180|SYKC_YEAST Lysine--tRNA ligase, cytoplasmic (Gene Name=KRS1)

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