Structure of PDB 7f5x Chain A

Receptor sequence
>7f5xA (length=236) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PTFTERSQLKYARRLVVKLGSAVITREDNHGLALGRLASIVEQVAECHLE
GREVMMVTSGAVAFGKQKLAQELLMSLSMRPRAAAAVGQSGLMSLYDAMF
AQYGVKIAQVLVTKPDFYNEETRNNLFCTLSELISLNIVPIINTNDAVSP
DNDSLSAMLAAEVQADLLILMSDVDGIYNKPPWEDGAKLMHTYTSKVKAA
TWALDRGVSVVICNGMQEKAIKTIIGGRKVGTFFTE
3D structure
PDB7f5x Structural basis of dynamic P5CS filaments.
ChainA
Resolution3.5 Å
3D
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Enzymatic activity
Enzyme Commision number 1.2.1.41: glutamate-5-semialdehyde dehydrogenase.
2.7.2.11: glutamate 5-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GGL A S103 A105 N204 D207 S59 A61 N143 D146
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004349 glutamate 5-kinase activity
GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006561 proline biosynthetic process
GO:0008652 amino acid biosynthetic process
GO:0016310 phosphorylation
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f5x, PDBe:7f5x, PDBj:7f5x
PDBsum7f5x
PubMed35286254
UniProtQ9VNW6

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