Structure of PDB 7f4e Chain A

Receptor sequence
>7f4eA (length=278) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLAR
LKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKD
VLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKS
KLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREPQ
QPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLI
VHQYSDEFAEQLVEELGWQEDFEKILTA
3D structure
PDB7f4e Global profiling of regulatory elements in the histone benzoylation pathway.
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.286: protein acetyllysine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F67 I117 H135 V182 F184 G185 E186 L188 V228 Y229 P230 E236 F60 I110 H128 V175 F177 G178 E179 L181 V213 Y214 P215 E221
BS02 ZN A C143 C146 C170 C173 C136 C139 C163 C166
Gene Ontology
Molecular Function
GO:0017136 NAD-dependent histone deacetylase activity
GO:0051287 NAD binding
GO:0070403 NAD+ binding

View graph for
Molecular Function
External links
PDB RCSB:7f4e, PDBe:7f4e, PDBj:7f4e
PDBsum7f4e
PubMed35296687
UniProtP53686|HST2_YEAST NAD-dependent protein deacetylase HST2 (Gene Name=HST2)

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