Structure of PDB 7f49 Chain A

Receptor sequence
>7f49A (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
HDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVA
VVEYHDGSHAYIGLKDRKRPSELRRIASQVKYAGSQVASTSEVLKYTLFQ
IFSKIDRPEASRIALLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIG
PHANLKQIRLIEKQAPENKAFVLSSVDELEQQRDEIVSYLCDLAPEAP
3D structure
PDB7f49 The development and characterization of a long acting anti-thrombotic von Willebrand factor (VWF) aptamer
ChainA
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K599 F603 S607 Q628 R629 R632 N633 V635 R636 Y637 Q639 G640 K643 K644 K95 F99 S103 Q124 R125 R128 N129 V131 R132 Y133 Q135 G136 K139 K140
External links
PDB RCSB:7f49, PDBe:7f49, PDBj:7f49
PDBsum7f49
PubMed32011054
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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