Structure of PDB 7f42 Chain A

Receptor sequence
>7f42A (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
TCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERI
QNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSC
AGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKG
RAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
3D structure
PDB7f42 PARP15 catalytic domain in complex with Iniparib
ChainA
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 33E A H559 G560 Y591 A593 Y598 S599 Y604 L659 H81 G82 Y113 A115 Y120 S121 Y126 L181
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7f42, PDBe:7f42, PDBj:7f42
PDBsum7f42
PubMed
UniProtQ460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15 (Gene Name=PARP15)

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