Structure of PDB 7etx Chain A

Receptor sequence
>7etxA (length=472) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence]
NNLPTVLESIVEGRRGHLEEIRARIAHVDVDALPKSTRSLFDSLNQGRGG
ARFIMECKSASPSLGMIREHYQPGEIARVYSRYASGISVLCEPDRFGGDY
DHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILLMLSVLDDEEYA
ALAAEAARFDLDILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDR
SRRLSKLIPADAVLVSESGVRDTETVRQLGGHSNAFLVGSQLTSQENVDL
AARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETLQ
KIIAAEPNLRYVAVSRRTSGYKDLLVDGIFAVQIHAPLQDSVEAEKALIA
AVREEVGPQVQVWRAISMSSPLGAEVAAAVEGDVDKLILDAHEGGSGEVF
DWATVPAAVKAKSLLAGGISPDNAAQALAVGCAGLDINSGVEYPAGAGTW
AGAKDAGALLKIFATISTFHYL
3D structure
PDB7etx Crystal Structure and Functional Characterization of the Bifunctional N -(5'-Phosphoribosyl)anthranilate Isomerase-indole-3-glycerol-phosphate Synthase from Corynebacterium glutamicum
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.48: indole-3-glycerol-phosphate synthase.
5.3.1.24: phosphoribosylanthranilate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL A T40 R133 D138 T37 R130 D135
BS02 GOL A A339 L341 R367 A368 S370 A336 L338 R364 A365 S367
Gene Ontology
Molecular Function
GO:0004425 indole-3-glycerol-phosphate synthase activity
GO:0004640 phosphoribosylanthranilate isomerase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0016853 isomerase activity
Biological Process
GO:0000162 tryptophan biosynthetic process
GO:0006568 tryptophan metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7etx, PDBe:7etx, PDBj:7etx
PDBsum7etx
PubMed34657425
UniProtP06560|TRPC_CORGL Tryptophan biosynthesis protein TrpCF (Gene Name=trpC)

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