Structure of PDB 7epe Chain A

Receptor sequence
>7epeA (length=389) Species: 882,9606 [Search protein sequence]
GDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGV
FLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTYRIARIFGA
KALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDL
VLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFC
GAVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIPRFI
SPASQVAICLALISGQLLIVVAWLVVEAPGTGLRCNHRDASMLGSLAYNV
LLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSD
YRVQTTTMCVSVSLSGSVVLGCLFAPKLYIILFQPQKNV
3D structure
PDB7epe Structures of human mGlu2 and mGlu7 homo- and heterodimers.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A S1009 T1010 T1011 N1013 T1014 S1057 T1058 W1059 G1093 D1094 W1097 S108 T109 T110 N112 T113 S156 T157 W158 G192 D193 W196
BS02 J9R A L639 G640 F643 D725 S731 L732 N735 W773 F780 Y781 M794 S797 L76 G77 F80 D289 S295 L296 N299 W337 F344 Y345 M358 S361
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0009055 electron transfer activity
GO:0010181 FMN binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7epe, PDBe:7epe, PDBj:7epe
PDBsum7epe
PubMed34135509
UniProtP00323|FLAV_NITV2 Flavodoxin (Gene Name=DVU_2680);
Q14416|GRM2_HUMAN Metabotropic glutamate receptor 2 (Gene Name=GRM2)

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