Structure of PDB 7eob Chain A

Receptor sequence
>7eobA (length=349) Species: 10090 (Mus musculus) [Search protein sequence]
ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFD
YSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGK
SYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCER
VRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKPR
TVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTKKVSKISLVDLAGSE
RNINKSLTTLGKVISALAEMFIPYRDSVLTWLLRENLGGNSRTAMVAALS
PADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLRD
3D structure
PDB7eob A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AF3 A S104 D248 S101 D245
BS02 ADP A R13 P14 Y67 G100 G102 K103 S104 Y105 R10 P11 Y64 G97 G99 K100 S101 Y102
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7eob, PDBe:7eob, PDBj:7eob
PDBsum7eob
PubMed35132656
UniProtP33173|KIF1A_MOUSE Kinesin-like protein KIF1A (Gene Name=Kif1a)

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