Structure of PDB 7eo9 Chain A

Receptor sequence
>7eo9A (length=351) Species: 10090 (Mus musculus) [Search protein sequence]
AGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFS
FDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGA
GKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYC
ERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNK
PRTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAG
SERNINKSLTTLGKVISALAEMFIPYRDSVLTWLLRENLGGNSRTAMVAA
LSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLR
D
3D structure
PDB7eo9 A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.
ChainA
Resolution2.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R13 Y67 T99 G100 A101 G102 K103 S104 Y105 K110 R12 Y66 T98 G99 A100 G101 K102 S103 Y104 K109
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7eo9, PDBe:7eo9, PDBj:7eo9
PDBsum7eo9
PubMed35132656
UniProtP33173|KIF1A_MOUSE Kinesin-like protein KIF1A (Gene Name=Kif1a)

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