Structure of PDB 7eip Chain A

Receptor sequence
>7eipA (length=966) Species: 585 (Proteus vulgaris) [Search protein sequence]
ATSNPAFDPKNLMQSEIYHFAQNNPLADFSSDKNSILTLSDKRSIMGNQS
LLWKWKGGSSFTLHKKLIVPTDKEASKAWGRSSTPVFSFWLYNEKPIDGY
LTIDFGEKLISTSQAGFKVKLDFTGWRAVGVSLNNDLELGAKVDSIRFKA
PSNVSQGEIYIDRIMFSVDDARYQWSDYQVKTRLSEPEIQFHNVKPQLPV
TPENLAAIDLIRQRLINEFVGKETNLALEENISKLKSDFDALNIHTLANG
GTQGRHLITDKQIIIYQPENLNSQDKQLFDNYVILGNYTTLMFNISRAYV
LEKDPTQKAQLKQMYLLMTKHLLDQGFVKGSALVTTHHWGYSSRWWYIST
LLMSDALKEANLQTQVYDSLLWYSREFKSSFDMKVSADSSDLDYFNTLSR
QHLALLLLEPDDQKRINLVNTFSHYITGALTQVPPGGKDGLRPDGTAWRH
EGNYPGYSFPAFKNASQLIYLLRDTPFSVGESGWNNLKKAMVSAWIYSNP
EVGLPLAGRHPFNSPSLKSVAQGYYWLAMSAKSSPDKTLASIYLAISDKT
QNESTAIFGETITPASLPQGFYAFNGGAFGIHRWQDKMVTLKAYNTNVWS
SEIYNKDNRYGRYQSHGVAQIVSNGSQLSQGYQQEGWDWNRMQGATTIHL
PLKDLDSPKPHTLMQRGERGFSGTSSLEGQYGMMAFDLIYPANLERFDPN
FTAKKSVLAADNHLIFIGSNINSSDKNKNVETTLFQHAITPTLNTLWING
QKIENMPYQTTLQQGDWLIDSNGNGYLITQAEKVNVSRQHQVSAENKNRQ
PTEGNFSSAWIDHSTRPKDASYEYMVFLDATPEKMGEMAQKFRENNGLYQ
VLRKDKDVHIILDKLSNVTGYAFYQPASIEDKWIKKVNKPAIVMTHRQKD
TLIVSAVTPDLNMTRQKAATPVTINVTINGKWQSSEVKYQVSGDNTELTF
TSYFGIPQEIKLSPLP
3D structure
PDB7eip Substrate specificity of Chondroitinase ABC I based on analyses of biochemical reactions and crystal structures in complex with disaccharides.
ChainA
Resolution1.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.20: chondroitin-sulfate-ABC endolyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A H43 M70 Q73 D211 H19 M46 Q49 D162
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0030246 carbohydrate binding
GO:0034000 chondroitin-sulfate-ABC endolyase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006027 glycosaminoglycan catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7eip, PDBe:7eip, PDBj:7eip
PDBsum7eip
PubMed34392362
UniProtP59807|CABC1_PROVU Chondroitin sulfate ABC endolyase

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