Structure of PDB 7ei0 Chain A

Receptor sequence
>7ei0A (length=241) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
QMNYEEVIKKYKGNENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGS
VESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICT
DDDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISV
AVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYY
IIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
3D structure
PDB7ei0 New insights of falcipain 2 structure from Plasmodium falciparum 3D7 strain.
ChainA
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.22.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EDO A E5 K135 E138 E5 K135 E138
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7ei0, PDBe:7ei0, PDBj:7ei0
PDBsum7ei0
PubMed34974303
UniProtQ8I6U4|FPC2A_PLAF7 Falcipain-2a (Gene Name=FP2A)

[Back to BioLiP]