Structure of PDB 7e9k Chain A

Receptor sequence
>7e9kA (length=527) Species: 9913 (Bos taurus) [Search protein sequence]
PAPALRIDYPKALQILTEGGTHMVCTGRTHTDRLCRFKWLCYSSEAEEFI
FFHGNASVMLPSLGSRRFQPALLDLSTVEDHNTQYFNFVELPAAALRFMP
KPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAREARLFFM
EGWGEGAHFDLYKLLSPKQPLLRAQLKALGRLLCFSHAFVGLSKVTTWYQ
YGFVQPQGPKANILVSGNEIRQFAHFLMEKLNVSEEYILVFSRTQNRLIL
NEAELLLALAQEFQMKTVTVSLEDHAFADVVRLVSNASMLVSMHGAQLVT
ALFLPRGAAVVELFPYAVNPDHYTPYKTLATLPGMDLQYIAWQNTMPENT
VTHPERPWDQGGIAHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTK
VDIPSLIQTIRRVVKGHPGPRKQKWTVSLYPGKVREARCQASVASEARLS
VSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYMLALQNHTFTENIKPF
TTYLVWIRCIFNKTLLGPFADVLVCST
3D structure
PDB7e9k The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on alpha-dystroglycan.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.312: protein O-mannose beta-1,4-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H125 N126 T127 F159 N160 D162 W197 F247 C437 H81 N82 T83 F115 N116 D118 W153 F203 C386
BS02 UDP A N163 L164 R294 Q296 N297 R298 E324 A347 Y447 N119 L120 R243 Q245 N246 R247 E273 A296 Y396
Gene Ontology
Molecular Function
GO:0008375 acetylglucosaminyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0097363 protein O-acetylglucosaminyltransferase activity
Biological Process
GO:0001764 neuron migration
GO:0006486 protein glycosylation
GO:0006493 protein O-linked glycosylation
GO:0035269 protein O-linked mannosylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7e9k, PDBe:7e9k, PDBj:7e9k
PDBsum7e9k
PubMed33893702
UniProtQ5NDF2|PMGT2_BOVIN Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (Gene Name=POMGNT2)

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