Structure of PDB 7e74 Chain A

Receptor sequence
>7e74A (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
CTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFW
LHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDL
FLNLEGKVNHLRCEKLTFNNPTTEFRYKLLRAGGVMV
3D structure
PDB7e74 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H56 F59 G77 Y78 A79 G80 D103 H52 F55 G73 Y74 A75 G76 D99
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:7e74, PDBe:7e74, PDBj:7e74
PDBsum7e74
PubMed36272410
UniProtQ03111|ENL_HUMAN Protein ENL (Gene Name=MLLT1)

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