Structure of PDB 7e5c Chain A

Receptor sequence

>7e5cA (length=439) Species: 1452721 (Pseudoalteromonas lipolytica SCSIO 04301)

DKLAVLYAEHIATLQQRTRTITEREGLEGLVIHSGQAKRQFLDWMYYPFK
VNPQFKAWLPVIDNPHCWIVVDGASKPKLIFYRPVDFWHKVPDEPRDFWA
EYFDIELLVQPDQVEKLLPYDKANYAYIGEYLEVAQALGFSIMNPEPVMN
YLHFHRAYKTQYELECLRQANRIAVEGHKAARDTFFNGGSEFDIQHAYLM
ATRQSENEMPYGNIVALNENCAIYLYTHFEPTAPHTHHSFLIDAGANFNG
YAADITRTYDFKKSGEFSDLIQVMTEHQIALGKALKPGLLYGELHLECHQ
RVAQVLSDFNIVKLPAADIVERGITSTFFPHGLGHHLGLQVIDMGGFMAD
ESGTHQAPPEGHPFLRCTRLIEKNQVFTIEPGLYFIDSLLGDLAQTDNKQ
FINWEKVEEFKPFGGIRIEDNIIVHEDSLENMTRDLHLD

3D structure

• PDB: 7e5c Structure-based redesign of the bacterial prolidase active-site pocket for efficient enhancement of methyl-parathion hydrolysis
• Chain: A
• Resolution: 2.22 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MN	A	D244 D255 E420	D243 D254 E419
BS02	MN	A	D255 H336 T379 E381 E420	D254 H335 T378 E380 E419

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Nov 25 05:49:02 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7e5c', asym_id = 'A', title = 'Structure-based redesign of the bacterial prolid...icient enhancement of methyl-parathion hydrolysis'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7e5c', asym_id='A', title='Structure-based redesign of the bacterial prolid...icient enhancement of methyl-parathion hydrolysis')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0016795', uniprot = '', pdbid = '7e5c', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0016795', uniprot='', pdbid='7e5c', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>