Structure of PDB 7e4u Chain A

Receptor sequence
>7e4uA (length=176) Species: 8175 (Sparus aurata) [Search protein sequence]
AGNAQIGKLAPDFTAKAVMPDGQFKDLKMSDYRGKYVVFFFYPLDFTFVC
PTEIIAFSDAADDFKKIGCEVIAASVDSHFSHLAWINTPRKQGGLGTMKI
PLVSDTRRTISTDYGVLKEDDGIAYRGLFIIDDKGILRQITINDLPVGRS
VEETLRLVQAFQFTDKHGEVCPAGWK
3D structure
PDB7e4u Crystal structure of Peroxiredoxin-1
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.24: thioredoxin-dependent peroxiredoxin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Y38 G70 Y36 G68
BS02 CA A D107 R109 D105 R107
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0008379 thioredoxin peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0051920 peroxiredoxin activity
GO:0140824 thioredoxin-dependent peroxiredoxin activity
Biological Process
GO:0006979 response to oxidative stress
GO:0019430 removal of superoxide radicals
GO:0033554 cellular response to stress
GO:0042744 hydrogen peroxide catabolic process
GO:0045321 leukocyte activation
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7e4u, PDBe:7e4u, PDBj:7e4u
PDBsum7e4u
PubMed
UniProtA0A671UQR2

[Back to BioLiP]