Structure of PDB 7e38 Chain A

Receptor sequence
>7e38A (length=313) Species: 93608 (Sinopodophyllum hexandrum) [Search protein sequence]
PLRLPVIDLSMKNLKPGTTSWNSVRTQVREALEEYGCFEAVIDAVSPELQ
KAVCNKGHELLNLPLETKMLNGNKPEYDGFTSIPNLNEGMGVGRITDLEK
VERFTNLMWPEGNKDFCETVYSYGKRMAEVDHILKMMVFESFGMEKHFDS
FCESTNYLLHFMRYQQPGKDGRSPALSLHKDKSILTIVNQNDVKGLEFET
KDGEWILPTADNHIVLLGDCFMAWSNGRLHSPLHRVTLVANQARLSTSSF
SFPKDIIETPAELVDEEHPLLFNPFEITELLAYCFTKEGAKAVCDLKQYK
AYTGALEHHHHHH
3D structure
PDB7e38 Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.20.8: (-)-deoxypodophyllotoxin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H184 D186 H239 H179 D181 H234
BS02 YTC A H165 M167 L181 H184 K187 F255 F257 F290 V298 H160 M162 L176 H179 K182 F250 F252 F285 V293
BS03 YTN A H165 M167 L181 H184 D186 K187 F290 V298 H160 M162 L176 H179 D181 K182 F285 V293
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0009611 response to wounding
GO:0009699 phenylpropanoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7e38, PDBe:7e38, PDBj:7e38
PDBsum7e38
PubMed34969844
UniProtA0A0N9HQ36|2ODD_SINHE Deoxypodophyllotoxin synthase (Gene Name=2-ODD)

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