Structure of PDB 7e2e Chain A

Receptor sequence
>7e2eA (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNALVSHLLVVEPEKLYAMPDHLPAVATLCDLFDREIVVTISWAKSIPG
FSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGAR
AAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAV
EQLREALHEALLEYEAGRRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK
VPMHKLFLEMLEAMMD
3D structure
PDB7e2e Discovery of a Novel Class of ERR alpha Agonists.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K340 L350 M354 Q358 L509 E512 K46 L56 M60 Q64 L206 E209
BS02 HVO A C325 F328 F382 F495 C31 F34 F88 F192
External links
PDB RCSB:7e2e, PDBe:7e2e, PDBj:7e2e
PDBsum7e2e
PubMed34055231
UniProtP11474|ERR1_HUMAN Steroid hormone receptor ERR1 (Gene Name=ESRRA)

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