Structure of PDB 7e1x Chain A

Receptor sequence
>7e1xA (length=378) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
DEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVW
LLLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILS
IAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRR
RKLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSG
WTPRYQGETIYLARATGTEDGPPFIKMRPEDMDAGGMETVFPWRESDGDG
TTVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFAF
TKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQL
PITIDTDGYLVANGDFVEPVGPAFWERT
3D structure
PDB7e1x Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.
ChainA
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES A C353 H355 C358 C372 H375 S377 C304 H306 C309 C323 H326 S328
BS02 MQ9 A F207 F222 F158 F173
BS03 9YF A I227 K228 N229 I178 K179 N180
BS04 9YF A W231 W246 E425 W182 W197 E376
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Cellular Component
External links
PDB RCSB:7e1x, PDBe:7e1x, PDBj:7e1x
PDBsum7e1x
PubMed34819223
UniProtP9WH23|QCRA_MYCTU Cytochrome bc1 complex Rieske iron-sulfur subunit (Gene Name=qcrA)

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