Structure of PDB 7e1s Chain A

Receptor sequence

>7e1sA (length=366) Species: 210 (Helicobacter pylori) [Search protein sequence]

HHHMVSTLKPLKIGKHTIKFPIFQGGMGVGISWDELAGNVAKEGALGVIS
AVGTGYYKNMRFVERIVAKKPFEALNFYSKKALNEIFANARKICGNNPLG
ANILYAINDYGRVLRDSCEAGANIIITGAGLPTNMPEFAKDFSDVALIPI
ISSAKALKILCKRWSDRYKRIPDAFIVEGPLSGGHQGFKYEDCFKEEFRL
ENLVPKVVEASKEWGNIPIIAAGGIWDRKDIDTMLSLGASGVQMATRFLG
TKECDAKVYADLLPTLKKEDILLIKSPVGYPARAINTGVIKRIEEGNAPK
IACVSNCVAPCNRGEEAKKVGYCIADGLGRSYLGNREEGLYFTGANGYRV
DKIISVHELIKELTEG

3D structure

PDB

7e1s Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis.

Chain

Resolution

2.31 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FMN	A	G22 G23 M24 G25 N99 L101 E175 G180 G220 G221 Q240 M241 A242 T243	G25 G26 M27 G28 N102 L104 E178 G183 G223 G224 Q243 M244 A245 T246
BS02	SF4	A	C300 N303 C304 V305 C308 G311 A314 C320 I321	C303 N306 C307 V308 C311 G314 A317 C323 I324
BS03	66S	A	L101 A126 G127 I147 I148 S149 E175 H182 G184 Y277 L325	L104 A129 G130 I150 I151 S152 E178 H185 G187 Y280 L328

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0018580	nitronate monooxygenase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:7e1s, PDBe:7e1s, PDBj:7e1s
PDBsum	7e1s
PubMed	34836944
UniProt	B5Z7D6

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