Structure of PDB 7e0d Chain A

Receptor sequence

>7e0dA (length=604) Species: 196112 (Streptomyces sp. X-119-6)

MTYEQLARELLLVGPAPTNEDLKLRYLDVLIDNGLNPPGPPKRILIVGAG
IAGLVAGDLLTRAGHDVTILEANANRVGGRIKTFHAKKGEPSPFADPAQY
AEAGAMRLPSFHPLTLALIDKLGLKRRLFFNVDIDPQTGNQDAPVPPVFY
KSFKDGKTWTNGAPSPEFKEPDKRNHTWIRTNREQVRRAQYATDPSSINE
GFHLTGCETRLTVSDMVNQALEPVRDYYSVKQDDGTRVNKPFKEWLAGWA
DVVRDFDGYSMGRFLREYAEFSDEAVEAIGTIENMTSELHLAFFHSFLGR
SDIDPRATYWEIEGGSRMLPETLAKDLRDQIVMGQRMVRLEYYDPGTGPG
GPAVAIQTVPEGAATQTWTGDLAIVTIPFSSLRFVKVTPPFSYKKRRAVI
ETHYDQATKVLLEFSRRWWEFTEADWKRELDAIAPGLYDYYQQWGEDDAE
AAGGVRPATNAYGGGSTTDNPNRFMYYPSHPVPGTQGGVVLAAYSWSDDA
ARWDSFDDAERYGYALENLQSVHGRRIEVFYTGAGQTQSWLRDPYACGEA
AVYTPHQMTAFHLDVVRPEGPVYFAGEHVSLKHAWIEGAVETAVRAAIAV
NEAP

3D structure

• PDB: 7e0d A new l-arginine oxidase engineered from l-glutamate oxidase.
• Chain: A
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 1.4.3.11: L-glutamate oxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G65 I68 A69 E88 A89 G96 R97 G121 A122 M123 R124 R353 M354 I405 S409 W608 Y613 E617 G644 E645 A652 W653 I654 A657	G48 I51 A52 E71 A72 G79 R80 G104 A105 M106 R107 R336 M337 I377 S381 W540 Y545 E549 G576 E577 A584 W585 I586 A589
BS02	ARG	A	R124 E305 W564 E617 A652 W653	R107 E288 W496 E549 A584 W585

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0001716 L-amino-acid oxidase activity
• GO:0016491 oxidoreductase activity

Biological Process

• GO:0009063 amino acid catabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:7e0d, PDBe:7e0d, PDBj:7e0d
• PDBsum: 7e0d
• PubMed: 33764624
• UniProt: Q8L3C7|LGOX_STRSQ L-glutamate oxidase precursor (Gene Name=lgoX)