Structure of PDB 7dyw Chain A

Receptor sequence
>7dywA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
QSTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIA
GCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFD
QIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLV
QVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAP
FLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
3D structure
PDB7dyw 5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
ChainA
Resolution2.13 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HRL A W248 Y272 W310 I317 S318 H321 N327 K336 H400 V402 W68 Y92 W130 I137 S138 H141 N147 K156 H220 V222
BS02 MN A H321 D323 H400 H141 D143 H220
External links
PDB RCSB:7dyw, PDBe:7dyw, PDBj:7dyw
PDBsum7dyw
PubMed37527664
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

[Back to BioLiP]