Structure of PDB 7dyv Chain A

Receptor sequence
>7dyvA (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
STVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAG
CRTVPVEVGEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQ
DISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKY
IRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILS
PGEILFIPVKYWHYVRALDLSFSVSFWWS
3D structure
PDB7dyv 5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H321 D323 H400 H134 D136 H213
BS02 HRF A W248 Y272 W310 I317 S318 H321 N327 K336 W61 Y85 W123 I130 S131 H134 N140 K149
External links
PDB RCSB:7dyv, PDBe:7dyv, PDBj:7dyv
PDBsum7dyv
PubMed37527664
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

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