Structure of PDB 7dy7 Chain A

Receptor sequence
>7dy7A (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAPYAAALEHHHH
3D structure
PDB7dy7 Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation.
ChainA
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HOU A I116 S117 A121 D122 Y123 K124 I99 S100 A104 D105 Y106 K107
External links
PDB RCSB:7dy7, PDBe:7dy7, PDBj:7dy7
PDBsum7dy7
PubMed35188766
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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