Structure of PDB 7du5 Chain A

Receptor sequence
>7du5A (length=117) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MRRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPV
TSNIAKVYPFQVLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAA
ELAQLDEALKLHLDLWS
3D structure
PDB7du5 Mechanistic Insight into the Peptide Binding Modes to Two M. tb MazF Toxins.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R24 N54 Y59 P60 F61 K77 H113 R23 N53 Y58 P59 F60 K76 H112
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006402 mRNA catabolic process
GO:0016075 rRNA catabolic process
GO:0044003 symbiont-mediated perturbation of host process
GO:0045926 negative regulation of growth

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Molecular Function
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Biological Process
External links
PDB RCSB:7du5, PDBe:7du5, PDBj:7du5
PDBsum7du5
PubMed33925254
UniProtP71650|MAZF9_MYCTU Endoribonuclease MazF9 (Gene Name=mazF9)

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