Structure of PDB 7dtn Chain A

Receptor sequence
>7dtnA (length=218) Species: 615 (Serratia marcescens) [Search protein sequence]
SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFT
AKDTEKLVTWFVERGYKIKGSISSHFHSESTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERK
ILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGD
ASLLKLTLEQAVKGLNES
3D structure
PDB7dtn Crystal Structures of Metallo-beta-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H77 H79 E81 H139 C158 H75 H77 E79 H137 C156
BS02 ZN A E81 C158 H197 E79 C156 H195
BS03 FLC A H79 E81 H139 C158 K161 G166 N167 H197 H77 E79 H137 C156 K159 G164 N165 H195
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process
GO:0046677 response to antibiotic
Cellular Component
GO:0042597 periplasmic space

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External links
PDB RCSB:7dtn, PDBe:7dtn, PDBj:7dtn
PDBsum7dtn
PubMed34242022
UniProtP52699|BLAB_SERMA Metallo-beta-lactamase type 2

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