Structure of PDB 7dlr Chain A

Receptor sequence
>7dlrA (length=423) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVE
LRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTP
DKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILN
GGAHADTAVDIQAFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTG
LGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTD
GTGYVFETTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASI
GDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTL
AHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQ
LLRIEEALGDAARYAGDLAFPRF
3D structure
PDB7dlr Mycobacterium tuberculosis enolase mutant - E163A
ChainA
Resolution2.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PEP A K335 H363 R364 S365 K386 K334 H362 R363 S364 K385
BS02 MG A D241 E283 D310 D241 E282 D309
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009986 cell surface

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7dlr, PDBe:7dlr, PDBj:7dlr
PDBsum7dlr
PubMed37860976
UniProtP9WNL1|ENO_MYCTU Enolase (Gene Name=eno)

[Back to BioLiP]