Structure of PDB 7dj2 Chain A

Receptor sequence
>7dj2A (length=492) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
REHWATRLGLILAMAGNAVGLCNFLRFPVQAAENGGGAFMIPYIIAFLLV
GIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVV
AIYYVYIESWTLGFAIKFLVGLVPEPPPNATDPDSILRPFKEFLYSYIGV
PKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFI
LAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFT
LSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVA
FFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLT
SSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMD
FWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRY
ITPAFLAVLLVVWHWTVWITRFYIIGLFLFLTFLVFLAERRR
3D structure
PDB7dj2 Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 LEU A A22 G24 C26 N27 Y108 F253 T254 S256 F259 A18 G20 C22 N23 Y104 F249 T250 S252 F255
BS02 NA A G20 V23 G24 A351 T354 S355 G16 V19 G20 A347 T350 S351
Gene Ontology
Biological Process
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7dj2, PDBe:7dj2, PDBj:7dj2
PDBsum7dj2
PubMed33811858
UniProtO67854

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