Structure of PDB 7dic Chain A

Receptor sequence
>7dicA (length=646) Species: 243273 (Mycoplasmoides genitalium G37) [Search protein sequence]
KKLQGILTLGNKNSGFIRSLDDDKTVYYVHYSNLTGALDGDLVEFCKLDK
PQFGDKFDAAVITILKRARILYAGNFLVDQNEFALEYKIVADNPRFYLTM
IVNPDSIPNNLASNTKIAFQIDEYDPDNNLCKVSVQQVLGNNDDPLINIK
AIMLDNSIVFETNDVVEQHANKLSFDTEEQHKAYRQDLTDLAFVTVDPTT
SKDLADAIYVKTIPTGFVLYVAIADVAHYVNRNSEIDIEAKHKTSSIYLP
GHYVVPMLPEQLSNQLCSLNPAQKRYVVVCEISFDNQGRIKTNKLYPATI
ISKNRFSYDQVNKWLNNKSELNCDETVINSLKAAFTLSDLIQAQRQKRGT
IDLSHKETEIVVDEHYFPIKINFLVHDKAETMIENLMVVANETVAWVLTN
NKIALPYRVHPRPSKKKLQSLIETVGELNITKPQFNLDTVTSSQIASWLN
ENKDNPSYEIFVILLLRTLGKAFYSVNPLMHFSIGSNHYTHFTSPIRRYI
DLTIHRLLWMHLFTPDQFTDNERDQLKQELEKIADTVNDTEIKIINCERN
ANDYLTTLLLSKQIGKTFSGFISAITSFGIFMRMDENNFDGLIKITTIPD
DFFIFEKEKMVLKGRKTNKVYKIGDRLEAKLSEIDFIQKRAILTLI
3D structure
PDB7dic Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
ChainA
Resolution2.242 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D276 D282 A284 D285 Y387 R576
Catalytic site (residue number reindexed from 1) D197 D203 A205 D206 Y308 R497
Enzyme Commision number 3.1.13.1: exoribonuclease II.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
Biological Process
GO:0006402 mRNA catabolic process
GO:0016070 RNA metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dic, PDBe:7dic, PDBj:7dic
PDBsum7dic
PubMed33788943
UniProtP47350|RNR_MYCGE Ribonuclease R (Gene Name=rnr)

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