Structure of PDB 7dg2 Chain A

Receptor sequence
>7dg2A (length=231) Species: 8355 (Xenopus laevis) [Search protein sequence]
MDRINESHQRFLQALMSHGIMEGSAVRALHRHCCELHKVHYMHDKLDDFV
GVLNRHLQPLFMTIEKGVGEEDGLTYYALVNRVENDITKMASDYAENELE
LFRKTMELIILSDNGFATSISILNLADELQSKKMKKKEVEQLLQSFVQEK
WLIGRNGEYTLHTRCIMELEHYIRNTYQDVAKICNVCRKVAIQSQLCENC
GIPLHLQCAGKYFHKANPTCPNCNESWPHEI
3D structure
PDB7dg2 Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.
ChainA
Resolution1.7 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C185 C188 H206 C209 C184 C187 H205 C208
BS02 ZN A C198 C201 C222 C225 C197 C200 C220 C223
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0030915 Smc5-Smc6 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dg2, PDBe:7dg2, PDBj:7dg2
PDBsum7dg2
PubMed33676928
UniProtQ6PAF4|NSE1_XENLA Non-structural maintenance of chromosomes element 1 homolog (Gene Name=nsmce1)

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