Structure of PDB 7dbs Chain A

Receptor sequence
>7dbsA (length=252) Species: 5664 (Leishmania major) [Search protein sequence]
CPPNIHFLEEVTSTMDVARTMRATAGGKAFAVVAAEQTAGRGTGGRTWTS
PKGNLYMTVGVPQLGCLKEELVPVLPLICGLACRRAVLEVLHLDGALAKA
SVAADAAKAVATKWPNDIIYNHKKIGGTLIESDGDYLIIGIGMNIAVAPQ
MDAGREATMINTIAEDFGVKSCPPRDLANAIWCHLFDICSSPEWTRELVI
ESFDKVMDKSLKLHKRLPGGRDPEELTAVSLNSWGHLKVRHADGTVEDLS
AE
3D structure
PDB7dbs Leishmania major biotin protein ligase forms a unique cross-handshake dimer.
ChainA
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.15: biotin--[biotin carboxyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BTN A T18 M19 Q41 G44 R45 T47 W52 M61 K131 I148 G149 T14 M15 Q37 G40 R41 T43 W48 M57 K124 I141 G142
Gene Ontology
Molecular Function
GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity
GO:0016874 ligase activity
Biological Process
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dbs, PDBe:7dbs, PDBj:7dbs
PDBsum7dbs
PubMed33825711
UniProtQ4Q6F6

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