Structure of PDB 7das Chain A

Receptor sequence
>7dasA (length=674) Species: 10090 (Mus musculus) [Search protein sequence]
NLYFQSQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTN
FTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFV
FCTNLTELDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQL
ENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTI
GKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSG
LKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYG
LSNLRYLSLKRAFTKQSASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSN
TFTGLVSLKYLSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIA
NGTFSWLGQLRILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLST
SSFALVPSLQRLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINE
DLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNG
LDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLIT
SVEKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELST
HYLCNTPHHYYGFPLKLFDTSSCK
3D structure
PDB7das Endosomal lncRNA Rmrp is required for TLR3 innate sensing by engaging TLR3 dimerization
ChainA
Resolution3.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K42 H61 N62 F85 N86 H109 E111 R490 N516 N518 H540 N542 S572 K21 H40 N41 F64 N65 H88 E90 R466 N492 N494 H516 N518 S548
External links
PDB RCSB:7das, PDBe:7das, PDBj:7das
PDBsum7das
PubMed
UniProtQ99MB1|TLR3_MOUSE Toll-like receptor 3 (Gene Name=Tlr3)

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