Structure of PDB 7d9i Chain A

Receptor sequence

>7d9iA (length=579) Species: 208964 (Pseudomonas aeruginosa PAO1)

YYPPALTGLRGSHPGAFEVAHQMGWEKKTFDVDHLPIEEEYDLVVVGGGI
SGLAAAWFYRERHPAARILVIENHDDFGGHAKRNEFQAGGRTILGYGGSE
SLQSPNALYSEDAKHLLKRLGVELKRFETAFDTDFYPGLGLSRAVFFDKA
SFGVDKLVSGDPTPMVADEVPRDRLNARSWRAFIGDFPLSREDREALIAL
YESPRDYLAGKSVEEKETYLAKTSYRDYLLKNVGLSETSVKYFQGRSNAF
SALGADALPAADAYAAGFPGFDALGLPQPMDEPYIYHFPDGNASLARLMV
RDLIPAVAPGRGMEDIVMARFDYSKLDLAGHPVRLRLNSTAVSVRNRAGG
VDVGYSRAGRLHRVRGKHCVMACYNMMVPYLLRDLSEEQAHALSQNVKFP
LVYTKVLLRNWQAWKTLGIHEIYAPTLPYSRIKLDFPVDLGSYRHPRDPR
QPIGVHMVYVPTTPNAGMDARTQARVGRSKLYAMSFEQLEKDIRDQLQAM
LGPAGFDHRRDITGITVNRWSHGYSYFMNTLYDDEAESEALMELARSKVG
NVAIANSDAAWDAYAHAAIDQAVRAVREL

3D structure

• PDB: 7d9i Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.
• Chain: A
• Resolution: 2.1 Å

Enzymatic activity

• Enzyme Commision number: 1.5.99.6: spermidine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V79 G80 G82 S84 E105 N106 H107 G112 H113 G131 S132 E133 S134 A381 C413 Y414 M417 Y443 G563 Y564 N596 S597 A603 Y604 A605 A608	V46 G47 G49 S51 E72 N73 H74 G79 H80 G98 S99 E100 S101 A341 C373 Y374 M377 Y403 G523 Y524 N556 S557 A563 Y564 A565 A568
BS02	HEM	A	S45 F50 A53 H54 W58 N106 Y414 M416 M417 Y420 R515 R518 S519 R559 S561 H562	S12 F17 A20 H21 W25 N73 Y374 M376 M377 Y380 R475 R478 S479 R519 S521 H522

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:7d9i, PDBe:7d9i, PDBj:7d9i
• PDBsum: 7d9i
• PubMed: 34741591
• UniProt: Q9HXS8