Structure of PDB 7d9h Chain A

Receptor sequence

>7d9hA (length=572) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]

YYPPALTGLRGSHPGAFEVAHQMGWEKKTFDVDHLPIEEEYDLVVVGGGI
SGLAAAWFYRERHPAARILVIENHDDFGGHAKRNEFQAGGRTILGYGGSE
SLQSYSEDAKHLLKRLGVELKRFETAFDTDFYPGLGLSRAVFFDKASFGV
DKLVSGDPTPMVADEVPRDRLNARSWRAFIGDFPLSREDREALIALYESP
RDYLAGKSVEEKETYLAKTSYRDYLLKNVGLSETSVKYFQGRSNDFSALG
ADALPAADAYAAGFPGFDALGLPDEPYIYHFPDGNASLARLMVRDLIPAV
APGRGMEDIVMARFDYSKLDLAGHPVRLRLNSTAVSVRNRAGGVDVGYSR
AGRLHRVRGKHCVMACYNMMVPYLLRDLSEEQAHALSQNVKFPLVYTKVL
LRNWQAWKTLGIHEIYAPTLPYSRIKLDFPVDLGSYRHPRDPRQPIGVHM
VYVPTTPNAGMDARTQARVGRSKLYAMSFEQLEKDIRDQLQAMLGPAGFD
HRRDITGITVNRWSHGYSYFMNTLYDDEAESEALMELARSKVGNVAIANS
DAAWDAYAHAAIDQAVRAVREL

3D structure

PDB

7d9h Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.

Chain

Resolution

2.31 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.5.99.6: spermidine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G80 G82 S84 E105 N106 H107 G112 H113 G131 S132 E133 S134 A381 C413 Y414 M417 Y443 G563 Y564 N596 S597 A603 Y604 A605	G47 G49 S51 E72 N73 H74 G79 H80 G98 S99 E100 S101 A334 C366 Y367 M370 Y396 G516 Y517 N549 S550 A556 Y557 A558
BS02	HEM	A	S45 F50 A53 H54 W58 N106 Y414 M416 M417 Y420 R518 S519 Y522 R559 S561 H562	S12 F17 A20 H21 W25 N73 Y367 M369 M370 Y373 R471 S472 Y475 R512 S514 H515

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:7d9h, PDBe:7d9h, PDBj:7d9h
PDBsum	7d9h
PubMed	34741591
UniProt	Q9HXS8

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