Structure of PDB 7d9f Chain A

Receptor sequence

>7d9fA (length=591) Species: 208964 (Pseudomonas aeruginosa PAO1)

APGGRYYPPALTGLRGSHPGAFEVAHQMGWEKKTFDVDHLPIEEEYDLVV
VGGGISGLAAAWFYRERHPAARILVIENHDDFGGHAKRNEFQAGGRTILG
YGGSESLQSPNALYSEDAKHLLKRLGVELKRFETAFDTDFYPGLGLSRAV
FFDKASFGVDKLVSGDPTPMVADEVPRDRLNARSWRAFIGDFPLSREDRE
ALIALYESPRDYLAGKSVEEKETYLAKTSYRDYLLKNVGLSETSVKYFQG
RSNDFSALGADALPAADAYAAGFPGFDALGLPQPSEEAQAEMDEPYIYHF
PDGNASLARLMVRDLIPAVAPGRGMEDIVMARFDYSKLDLAGHPVRLRLN
STAVSVRNRAGGVDVGYSRAGRLHRVRGKHCVMACYNMMVPYLLRDLSEE
QAHALSQNVKFPLVYTKVLLRNWQAWKTLGIHEIYAPTLPYSRIKLDFPV
DLGSYRHPRDPRQPIGVHMVYVPTTPNAGMDARTQARVGRSKLYAMSFEQ
LEKDIRDQLQAMLGPAGFDHRRDITGITVNRWSHGYSYFMNTLYDDEAES
EALMELARSKVGNVAIANSDAAWDAYAHAAIDQAVRAVREL

3D structure

• PDB: 7d9f Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.
• Chain: A
• Resolution: 1.85 Å

Enzymatic activity

• Enzyme Commision number: 1.5.99.6: spermidine dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G80 G82 S84 E105 N106 H107 G112 H113 G131 S132 E133 S134 T380 A381 C413 Y414 M417 Y443 G563 Y564 N596 S597 A603 Y604 A605 A608	G52 G54 S56 E77 N78 H79 G84 H85 G103 S104 E105 S106 T352 A353 C385 Y386 M389 Y415 G535 Y536 N568 S569 A575 Y576 A577 A580
BS02	HEM	A	S45 F50 A53 H54 W58 H107 Y414 M416 M417 Y420 R518 S519 Y522 R559 S561 H562	S17 F22 A25 H26 W30 H79 Y386 M388 M389 Y392 R490 S491 Y494 R531 S533 H534

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:7d9f, PDBe:7d9f, PDBj:7d9f
• PDBsum: 7d9f
• PubMed: 34741591
• UniProt: Q9HXS8