Structure of PDB 7d8i Chain A

Receptor sequence
>7d8iA (length=174) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence]
SIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESD
GRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKY
IDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQW
IEQKKGPFAPDFIKVWKERYKKIR
3D structure
PDB7d8i The structural mechanism for the nucleoside tri- and diphosphate hydrolysis activity of Ntdp from Staphylococcus aureus.
ChainA
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.6: nucleoside diphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A H25 R26 W28 N45 I77 M79 Y88 D110 H21 R22 W24 N41 I73 M75 Y84 D106
BS02 CA A N90 D106 D110 N86 D102 D106
BS03 CA A D108 D110 D123 E126 D104 D106 D119 E122
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0017110 nucleoside diphosphate phosphatase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7d8i, PDBe:7d8i, PDBj:7d8i
PDBsum7d8i
PubMed33955674
UniProtQ7A4T2|NTDP_STAAN Nucleoside triphosphate/diphosphate phosphatase (Gene Name=SA1684)

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