Structure of PDB 7d8d Chain A

Receptor sequence
>7d8dA (length=232) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MDVPADSHIKYEDAIDYWTDVDATVDGVLGGYGEGTVVPTMDVLGSNNFL
RKLKSRMLPQENNVKYAVDIGAGIGRVSKTMLHKHAAKIDLVEPVKPFIE
QMHVELAELKDKGQIGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLPDAEL
VAFLKRCIVGLQPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKFRQIFE
EAGLKLIASERQRGLPRELYPVRMYALKPMPN
3D structure
PDB7d8d Structural Basis for Peptide Binding of Alpha-N Terminal Methyltransferase from Saccharomyces cerevisiae
ChainA
Resolution1.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.244: protein N-terminal methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W18 L29 Y32 W140 P175 D182 D185 E218 L219 Y220 W18 L29 Y32 W140 P175 D182 D185 E218 L219 Y220
BS02 SAH A W18 G71 G73 R76 V77 E93 P94 F98 M123 Q124 W140 H144 W18 G71 G73 R76 V77 E93 P94 F98 M123 Q124 W140 H144
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0071885 N-terminal protein N-methyltransferase activity
Biological Process
GO:0002181 cytoplasmic translation
GO:0006480 N-terminal protein amino acid methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7d8d, PDBe:7d8d, PDBj:7d8d
PDBsum7d8d
PubMed
UniProtP38340|NTM1_YEAST Alpha N-terminal protein methyltransferase 1 (Gene Name=TAE1)

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