Structure of PDB 7d4s Chain A

Receptor sequence
>7d4sA (length=345) Species: 550 (Enterobacter cloacae) [Search protein sequence]
MELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTFL
QGSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKYY
PGKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTVN
SLEEQTDWRLNKSWTPNTVEDAPASEWKAHPLVLPDREKNEWGRTHPLAQ
IRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEHLIGNAL
DNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDVMARLTA
EDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLPG
3D structure
PDB7d4s Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
ChainA
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APC A S53 R56 D69 D71 Q210 Y250 V304 S53 R56 D69 D71 Q200 Y240 V294
BS02 APC A Q51 R109 L194 R197 R204 T205 Q51 R109 L184 R187 R194 T195
BS03 MG A D69 D71 D69 D71
BS04 MG A D69 D71 D121 D69 D71 D121
BS05 MG A N258 L260 N248 L250
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7d4s, PDBe:7d4s, PDBj:7d4s
PDBsum7d4s
PubMed33836064
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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